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Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy
Here, we report the hypoxia-responsive ionizable liposomes to deliver small interference RNA (siRNA) anticancer drugs, which can selectively enhance cellular uptake of the siRNA under hypoxic and low-pH conditions to cure glioma. For this purpose, malate dehydrogenase lipid molecules were synthesize...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Int J Nanomedicine |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Dove Medical Press
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5308568/ https://ncbi.nlm.nih.gov/pubmed/28223799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S125286 |
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