Efficient delivery of Notch1 siRNA to SKOV3 cells by cationic cholesterol derivative-based liposome

A novel cationic cholesterol derivative-based small interfering RNA (siRNA) interference strategy was suggested to inhibit Notch1 activation in SKOV3 cells for the gene therapy of ovarian cancer. The cationic cholesterol derivative, N-(cholesterylhemisuccinoyl-amino-3-propyl)-N, N-dimethylamine (DMA...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhao, Yun-Chun, Zhang, Li, Feng, Shi-Sen, Hong, Lu, Zheng, Hai-Li, Chen, Li-Li, Zheng, Xiao-Ling, Ye, Yi-Qing, Zhao, Meng-Dan, Wang, Wen-Xi, Zheng, Cai-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077131/
https://ncbi.nlm.nih.gov/pubmed/27799771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S115367
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