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Transcriptional Addiction in Cancer

Cancer arises from genetic alterations that invariably lead to dysregulated transcriptional programs. These dysregulated programs can cause cancer cells to become highly dependent on certain regulators of gene expression. Here we discuss how transcriptional control is disrupted by genetic alteration...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Bradner, James E., Hnisz, Denes, Young, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308559/
https://ncbi.nlm.nih.gov/pubmed/28187285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.013
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