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SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling

In Hedgehog (Hh) signaling, the GPCR-family protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation and ubiquitination, which ultimately change the cell surface accumulation of Smo. However, it is not clear whether Smo is regulated by other post-translational modifi...

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Publicat a:Sci Rep
Autors principals: Zhang, Jie, Liu, Yajuan, Jiang, Kai, Jia, Jianhang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307382/
https://ncbi.nlm.nih.gov/pubmed/28195188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42749
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