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SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling
In Hedgehog (Hh) signaling, the GPCR-family protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation and ubiquitination, which ultimately change the cell surface accumulation of Smo. However, it is not clear whether Smo is regulated by other post-translational modifi...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307382/ https://ncbi.nlm.nih.gov/pubmed/28195188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42749 |
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