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Smoothened regulation in response to Hedgehog stimulation

The Hedgehog (Hh) signaling pathway play critical roles in embryonic development and adult tissue homeostasis. A critical step in Hh signal transduction is how Hh receptor Patched (Ptc) inhibits the atypical G protein-coupled receptor Smoothened (Smo) in the absence of Hh and how this inhibition is...

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Bibliografiska uppgifter
I publikationen:Front Biol (Beijing)
Huvudupphovsmän: Jiang, Kai, Jia, Jianhang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787298/
https://ncbi.nlm.nih.gov/pubmed/26973699
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