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Casein Kinase 2 Promotes Hedgehog Signaling by Regulating both Smoothened and Cubitus Interruptus

Casein kinase 2 (CK2) is a typical serine/threonine kinase consisting of α and β subunits and has been implicated in many cellular and developmental processes. In this study, we demonstrate that CK2 is a positive regulator of the Hedgehog (Hh) signal transduction pathway. We found that inactivation...

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Bibliographische Detailangaben
Hauptverfasser: Jia, Hongge, Liu, Yajuan, Xia, Ruohan, Tong, Chao, Yue, Tao, Jiang, Jin, Jia, Jianhang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988328/
https://ncbi.nlm.nih.gov/pubmed/20876583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.174565
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