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Hrs Promotes Ubiquitination and Mediates Endosomal Trafficking of Smoothened in Drosophila Hedgehog Signaling

In Hedgehog (Hh) signaling, the seven-transmembrane protein Smoothened (Smo) acts as a signal transducer that is regulated by phosphorylation, ubiquitination, and cell surface accumulation. However, it is not clear how Smo cell surface accumulation and intracellular trafficking are regulated. Here,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fan, Junkai, Jiang, Kai, Liu, Yajuan, Jia, Jianhang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823941/
https://ncbi.nlm.nih.gov/pubmed/24244405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079021
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