Population pharmacokinetics and dosing recommendations for the use of deferiprone in children younger than 6 years

AIMS: Despite long clinical experience with deferiprone, there is limited information on its pharmacokinetics in children aged <6 years. Here we assess the impact of developmental growth on the pharmacokinetics of deferiprone in this population using a population approach. Based on pharmacokineti...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Maggio, Aurelio, Filosa, Aldo, Cosmi, Carlo, Mangiarini, Laura, Spino, Michael, Connelly, John, Ceci, Adriana, Della Pasqua, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Paediatric Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306498/
https://ncbi.nlm.nih.gov/pubmed/27641003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13134
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