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Effects of renal impairment on the pharmacokinetics of orally administered deferiprone

AIMS: In light of the growing recognition of renal disease in thalassemia, it is important to understand the impact of renal impairment on the pharmacokinetics of iron chelators. This study evaluated the pharmacokinetics and safety of the iron chelator deferiprone (DFP) in subjects with renal impair...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Fradette, Caroline, Pichette, Vincent, Sicard, Éric, Stilman, Anne, Jayashankar, Shalini, Tsang, Yu Chung, Spino, Michael, Tricta, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137824/
https://ncbi.nlm.nih.gov/pubmed/27276421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13037
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