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Pharmacokinetics of the novel oral prostacyclin receptor agonist selexipag in subjects with hepatic or renal impairment

AIM: The aim of the present study was to explore the effect of hepatic or renal dysfunction on the pharmacokinetics (PK), tolerability and safety of selexipag, an orally active prostacyclin receptor agonist. METHODS: Two prospective, open‐label studies evaluated the PK of selexipag and its active me...

詳細記述

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書誌詳細
出版年:Br J Clin Pharmacol
主要な著者: Kaufmann, Priska, Cruz, Hans G., Krause, Andreas, Ulč, Ivan, Halabi, Atef, Dingemanse, Jasper
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972153/
https://ncbi.nlm.nih.gov/pubmed/27062188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12963
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