Loading...

Effect of lopinavir/ritonavir on the pharmacokinetics of selexipag an oral prostacyclin receptor agonist and its active metabolite in healthy subjects

AIMS: This study investigated the effect of a fixed dose combination of lopinavir/ritonavir on the pharmacokinetics (PK) of selexipag and its active metabolite ACT-333679. METHODS: This was an open label, randomized, single centre, two way, crossover study. Twenty healthy male subjects were treated...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Kaufmann, Priska, Niglis, Séverine, Bruderer, Shirin, Segrestaa, Jérôme, Äänismaa, Päivi, Halabi, Atef, Dingemanse, Jasper
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594703/
https://ncbi.nlm.nih.gov/pubmed/25851691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12650
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!