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Model-Based Optimisation of Deferoxamine Chelation Therapy
PURPOSE: Here we show how a model-based approach may be used to provide further insight into the role of clinical and demographic covariates on the progression of iron overload. The therapeutic effect of deferoxamine is used to illustrate the application of disease modelling as a means to characteri...
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Publicado no: | Pharm Res |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4709373/ https://ncbi.nlm.nih.gov/pubmed/26555666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1805-0 |
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