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Model-Based Optimisation of Deferoxamine Chelation Therapy

PURPOSE: Here we show how a model-based approach may be used to provide further insight into the role of clinical and demographic covariates on the progression of iron overload. The therapeutic effect of deferoxamine is used to illustrate the application of disease modelling as a means to characteri...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Bellanti, Francesco, Del Vecchio, Giovanni C., Putti, Maria C., Cosmi, Carlo, Fotzi, Ilaria, Bakshi, Suruchi D., Danhof, Meindert, Della Pasqua, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709373/
https://ncbi.nlm.nih.gov/pubmed/26555666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1805-0
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