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Integration of PKPD relationships into benefit–risk analysis

AIM: Despite the continuous endeavour to achieve high standards in medical care through effectiveness measures, a quantitative framework for the assessment of the benefit–risk balance of new medicines is lacking prior to regulatory approval. The aim of this short review is to summarise the approache...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Bellanti, Francesco, van Wijk, Rob C, Danhof, Meindert, Della Pasqua, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631171/
https://ncbi.nlm.nih.gov/pubmed/25940398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12674
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