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Modelling and simulation as research tools in paediatric drug development

PURPOSE: Although practical and ethical constraints impose special requirements for the evaluation of treatment safety and efficacy in children, the main issue remains the empirical basis for patient stratification and dose selection at the early stage of the development of new chemical and biologic...

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Hlavní autoři: Bellanti, Francesco, Della Pasqua, Oscar
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082698/
https://ncbi.nlm.nih.gov/pubmed/21246352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-010-0974-3
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