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PBPK modeling and simulation in drug research and development

Physiologically based pharmacokinetic (PBPK) modeling and simulation can be used to predict the pharmacokinetic behavior of drugs in humans using preclinical data. It can also explore the effects of various physiologic parameters such as age, ethnicity, or disease status on human pharmacokinetics, a...

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Bibliografiska uppgifter
I publikationen:Acta Pharm Sin B
Huvudupphovsmän: Zhuang, Xiaomei, Lu, Chuang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125732/
https://ncbi.nlm.nih.gov/pubmed/27909650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.04.004
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