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Modelling and PBPK Simulation in Drug Discovery

Physiologically based pharmacokinetic (PBPK) models are composed of a series of differential equations and have been implemented in a number of commercial software packages. These models require species-specific and compound-specific input parameters and allow for the prediction of plasma and tissue...

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Podrobná bibliografie
Hlavní autoři: Jones, Hannah M., Gardner, Iain B., Watson, Kenny J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664888/
https://ncbi.nlm.nih.gov/pubmed/19280352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9088-1
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