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P-selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin1 in mice

BACKGROUND: P-selectin and thrombospondin1 (TSP1) have been suggested as counter ligands that may mediate GPIbα-dependent thrombus growth independently of VWF in vitro. However, residual thrombus formation still persists in Vwf (−/−)Tsp1(−/−) mice suggesting existence of other mechanisms that modula...

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Vydáno v:J Thromb Haemost
Hlavní autoři: Prakash, Prem, Nayak, Manasa K., Chauhan, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305620/
https://ncbi.nlm.nih.gov/pubmed/27943541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13586
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