Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor

Insulin and IGF-1 signaling are important for adipose tissue development and function, however their role in mature adipocytes is unclear. Mice with a tamoxifen-inducible knockout of insulin and/or IGF1 receptors (IR/IGF1R) demonstrate a rapid loss of white and brown fat due to increased lipolysis a...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Metab
Päätekijät: Sakaguchi, Masaji, Fujisaka, Shiho, Cai, Weikang, Winnay, Jonathon N., Konishi, Masahiro, O’Neil, Brian, Li, Mengyao, García-Martín, Rubén, Takahashi, Hirokazu, Hu, Jiang, Kulkarni, Rohit N., Kahn, C. Ronald
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304432/
https://ncbi.nlm.nih.gov/pubmed/28065828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.12.008
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