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Adipose-Derived Circulating miRNAs Regulate Gene Expression in Other Tissues
Adipose tissue is a major site of energy storage and plays a role in regulation of metabolism through release of adipokines. Here we show that mice with a fat-specific knockout of the miRNA-processing enzyme Dicer (ADicerKO), as well as humans with lipodystrophy, have major decreases in circulating...
में बचाया:
| में प्रकाशित: | Nature |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330251/ https://ncbi.nlm.nih.gov/pubmed/28199304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21365 |
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