Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

Kinases downstream of B-cell antigen receptor (BCR) represent attractive targets for therapy in non-Hodgkin lymphoma (NHL). As clinical responses vary, improved knowledge regarding activation and regulation of BCR signaling in individual patients is needed. Here, using phosphospecific flow cytometry...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Myklebust, June H., Brody, Joshua, Kohrt, Holbrook E., Kolstad, Arne, Czerwinski, Debra K., Wälchli, Sébastien, Green, Michael R., Trøen, Gunhild, Liestøl, Knut, Beiske, Klaus, Houot, Roch, Delabie, Jan, Alizadeh, Ash A., Irish, Jonathan M., Levy, Ronald
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2017
Sujets:
Lymphoid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301824/
https://ncbi.nlm.nih.gov/pubmed/28011673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-718494
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