Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T(reg) depletion

Despite the success of passive immunotherapy with monoclonal antibodies (mAbs), many lymphoma patients eventually relapse. Induction of an adaptive immune response may elicit active and long-lasting antitumor immunity, thereby preventing or delaying recurrence. Immunomodulating mAbs directed against...

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Main Authors: Houot, Roch, Goldstein, Matthew J., Kohrt, Holbrook E., Myklebust, June H., Alizadeh, Ash A., Lin, Jack T., Irish, Jonathan M., Torchia, James A., Kolstad, Arne, Chen, Lieping, Levy, Ronald
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2009
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765679/
https://ncbi.nlm.nih.gov/pubmed/19641184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-223958
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