Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T(reg) depletion

Despite the success of passive immunotherapy with monoclonal antibodies (mAbs), many lymphoma patients eventually relapse. Induction of an adaptive immune response may elicit active and long-lasting antitumor immunity, thereby preventing or delaying recurrence. Immunomodulating mAbs directed against...

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Главные авторы: Houot, Roch, Goldstein, Matthew J., Kohrt, Holbrook E., Myklebust, June H., Alizadeh, Ash A., Lin, Jack T., Irish, Jonathan M., Torchia, James A., Kolstad, Arne, Chen, Lieping, Levy, Ronald
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2009
Предметы:
Lymphoid Neoplasia
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765679/
https://ncbi.nlm.nih.gov/pubmed/19641184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-223958
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