Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling

Kinases downstream of B-cell antigen receptor (BCR) represent attractive targets for therapy in non-Hodgkin lymphoma (NHL). As clinical responses vary, improved knowledge regarding activation and regulation of BCR signaling in individual patients is needed. Here, using phosphospecific flow cytometry...

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Udgivet i:Blood
Main Authors: Myklebust, June H., Brody, Joshua, Kohrt, Holbrook E., Kolstad, Arne, Czerwinski, Debra K., Wälchli, Sébastien, Green, Michael R., Trøen, Gunhild, Liestøl, Knut, Beiske, Klaus, Houot, Roch, Delabie, Jan, Alizadeh, Ash A., Irish, Jonathan M., Levy, Ronald
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2017
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301824/
https://ncbi.nlm.nih.gov/pubmed/28011673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-718494
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