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CD137 stimulation enhances the vaccinal effect of anti-tumor antibodies

Some evidence suggests that monoclonal antibodies (mAb) can induce an adaptive immune response against tumor cells (“vaccinal effect”). Recently, we have shown that an anti-CD137 mAb can enhance the “vaccinal effect” of an anti-tumor mAb (cetuximab), thereby transforming a passive, monoclonal, short...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Houot, Roch, Kohrt, Holbrook
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292240/
https://ncbi.nlm.nih.gov/pubmed/25610724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.941740
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