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Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T(reg) depletion

Despite the success of passive immunotherapy with monoclonal antibodies (mAbs), many lymphoma patients eventually relapse. Induction of an adaptive immune response may elicit active and long-lasting antitumor immunity, thereby preventing or delaying recurrence. Immunomodulating mAbs directed against...

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Détails bibliographiques
Auteurs principaux: Houot, Roch, Goldstein, Matthew J., Kohrt, Holbrook E., Myklebust, June H., Alizadeh, Ash A., Lin, Jack T., Irish, Jonathan M., Torchia, James A., Kolstad, Arne, Chen, Lieping, Levy, Ronald
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765679/
https://ncbi.nlm.nih.gov/pubmed/19641184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-223958
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