Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by T(reg) depletion

Despite the success of passive immunotherapy with monoclonal antibodies (mAbs), many lymphoma patients eventually relapse. Induction of an adaptive immune response may elicit active and long-lasting antitumor immunity, thereby preventing or delaying recurrence. Immunomodulating mAbs directed against...

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Hlavní autoři: Houot, Roch, Goldstein, Matthew J., Kohrt, Holbrook E., Myklebust, June H., Alizadeh, Ash A., Lin, Jack T., Irish, Jonathan M., Torchia, James A., Kolstad, Arne, Chen, Lieping, Levy, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765679/
https://ncbi.nlm.nih.gov/pubmed/19641184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-223958
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