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mTORC1 signaling promotes limb bud cell growth and chondrogenesis

mTORC1 signaling has been shown to promote limb skeletal growth through stimulation of protein synthesis in chondrocytes. However, potential roles of mTORC1 in prechondrogenic mesenchyme have not been explored. In this study, we first deleted Raptor, a unique and essential component of mTORC1, in pr...

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Dades bibliogràfiques
Publicat a:J Cell Biochem
Autors principals: Jiang, Ming, Fu, Xuejie, Yang, Huilin, Long, Fanxin, Chen, Jianquan
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296292/
https://ncbi.nlm.nih.gov/pubmed/27606668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25728
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