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mTORC1 signaling promotes limb bud cell growth and chondrogenesis

mTORC1 signaling has been shown to promote limb skeletal growth through stimulation of protein synthesis in chondrocytes. However, potential roles of mTORC1 in prechondrogenic mesenchyme have not been explored. In this study, we first deleted Raptor, a unique and essential component of mTORC1, in pr...

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Podrobná bibliografie
Vydáno v:J Cell Biochem
Hlavní autoři: Jiang, Ming, Fu, Xuejie, Yang, Huilin, Long, Fanxin, Chen, Jianquan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296292/
https://ncbi.nlm.nih.gov/pubmed/27606668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25728
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