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mTORC1 signaling promotes limb bud cell growth and chondrogenesis

mTORC1 signaling has been shown to promote limb skeletal growth through stimulation of protein synthesis in chondrocytes. However, potential roles of mTORC1 in prechondrogenic mesenchyme have not been explored. In this study, we first deleted Raptor, a unique and essential component of mTORC1, in pr...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Jiang, Ming, Fu, Xuejie, Yang, Huilin, Long, Fanxin, Chen, Jianquan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296292/
https://ncbi.nlm.nih.gov/pubmed/27606668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25728
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