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mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis

Much of the mammalian skeleton is derived from a cartilage template that undergoes rapid growth during embryogenesis, but the molecular mechanism of growth regulation is not well understood. Signaling by mammalian target of rapamycin complex 1 (mTORC1) is an evolutionarily conserved mechanism that c...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Jianquan, Long, Fanxin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197614/
https://ncbi.nlm.nih.gov/pubmed/24948603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108811
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