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mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis
Much of the mammalian skeleton is derived from a cartilage template that undergoes rapid growth during embryogenesis, but the molecular mechanism of growth regulation is not well understood. Signaling by mammalian target of rapamycin complex 1 (mTORC1) is an evolutionarily conserved mechanism that c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197614/ https://ncbi.nlm.nih.gov/pubmed/24948603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.108811 |
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