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Bmp Induces Osteoblast Differentiation through both Smad4 and mTORC1 Signaling

The bone morphogenetic protein (Bmp) family of secreted molecules has been extensively studied in the context of osteoblast differentiation. However, the intracellular signaling cascades that mediate the osteoblastogenic function of Bmp have not been fully elucidated. By profiling mRNA expression in...

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Pubblicato in:Mol Cell Biol
Autori principali: Karner, Courtney M., Lee, Seung-Yon, Long, Fanxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288572/
https://ncbi.nlm.nih.gov/pubmed/27920253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00253-16
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