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WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation

WNT signaling controls many biological processes including cell differentiation in metazoans. However, how WNT reprograms cell identity is not well understood. We have investigated the potential role of cellular metabolism in WNT-induced osteoblast differentiation. WNT3A induces aerobic glycolysis k...

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書誌詳細
主要な著者: Esen, Emel, Chen, Jianquan, Karner, Courtney M., Okunade, Adewole L., Patterson, Bruce W., Long, Fanxin
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653292/
https://ncbi.nlm.nih.gov/pubmed/23623748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.017
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