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Increased glutamine catabolism mediates bone anabolism in response to WNT signaling

WNT signaling stimulates bone formation by increasing both the number of osteoblasts and their protein-synthesis activity. It is not clear how WNT augments the capacity of osteoblast progenitors to meet the increased energetic and synthetic needs associated with mature osteoblasts. Here, in cultured...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Karner, Courtney M., Esen, Emel, Okunade, Adewole L., Patterson, Bruce W., Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319407/
https://ncbi.nlm.nih.gov/pubmed/25562323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78470
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