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Increased glutamine catabolism mediates bone anabolism in response to WNT signaling
WNT signaling stimulates bone formation by increasing both the number of osteoblasts and their protein-synthesis activity. It is not clear how WNT augments the capacity of osteoblast progenitors to meet the increased energetic and synthetic needs associated with mature osteoblasts. Here, in cultured...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319407/ https://ncbi.nlm.nih.gov/pubmed/25562323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78470 |
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