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Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation

Developmental signals in metazoans play critical roles in inducing cell differentiation from multipotent progenitors. The existing paradigm posits that the signals operate directly through their downstream transcription factors to activate expression of cell type-specific genes, which are the hallma...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Karner, Courtney M., Esen, Emel, Chen, Jiakun, Hsu, Fong-Fu, Turk, John, Long, Fanxin
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933220/
https://ncbi.nlm.nih.gov/pubmed/27129247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.708578
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