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WNT-LRP5 signaling induces Warburg effect through mTORC2 activation during osteoblast differentiation
WNT signaling controls many biological processes including cell differentiation in metazoans. However, how WNT reprograms cell identity is not well understood. We have investigated the potential role of cellular metabolism in WNT-induced osteoblast differentiation. WNT3A induces aerobic glycolysis k...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653292/ https://ncbi.nlm.nih.gov/pubmed/23623748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.017 |
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