WNT7B Promotes Bone Formation in part through mTORC1

WNT signaling has been implicated in both embryonic and postnatal bone formation. However, the pertinent WNT ligands and their downstream signaling mechanisms are not well understood. To investigate the osteogenic capacity of WNT7B and WNT5A, both normally expressed in the developing bone, we engine...

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Main Authors: Chen, Jianquan, Tu, Xiaolin, Esen, Emel, Joeng, Kyu Sang, Lin, Congxin, Arbeit, Jeffrey M., Rüegg, Markus A., Hall, Michael N., Ma, Liang, Long, Fanxin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907335/
https://ncbi.nlm.nih.gov/pubmed/24497849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004145
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