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WNT7B Promotes Bone Formation in part through mTORC1

WNT signaling has been implicated in both embryonic and postnatal bone formation. However, the pertinent WNT ligands and their downstream signaling mechanisms are not well understood. To investigate the osteogenic capacity of WNT7B and WNT5A, both normally expressed in the developing bone, we engine...

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Detalhes bibliográficos
Main Authors: Chen, Jianquan, Tu, Xiaolin, Esen, Emel, Joeng, Kyu Sang, Lin, Congxin, Arbeit, Jeffrey M., Rüegg, Markus A., Hall, Michael N., Ma, Liang, Long, Fanxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907335/
https://ncbi.nlm.nih.gov/pubmed/24497849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004145
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