Peptide drugs accelerate BMP‐2‐induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling

Both W9 and OP3‐4 were known to bind the receptor activator of NF‐κB ligand (RANKL), inhibiting osteoclastogenesis. Recently, both peptides were shown to stimulate osteoblast differentiation; however, the mechanism underlying the activity of these peptides remains to be clarified. A primary osteobla...

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Detaylı Bibliyografya
Yayımlandı:Bioessays
Asıl Yazarlar: Sugamori, Yasutaka, Mise‐Omata, Setsuko, Maeda, Chizuko, Aoki, Shigeki, Tabata, Yasuhiko, Murali, Ramachandran, Yasuda, Hisataka, Udagawa, Nobuyuki, Suzuki, Hiroshi, Honma, Masashi, Aoki, Kazuhiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Primary Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094554/
https://ncbi.nlm.nih.gov/pubmed/27345003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600104
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