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mTORC1 signaling promotes limb bud cell growth and chondrogenesis

mTORC1 signaling has been shown to promote limb skeletal growth through stimulation of protein synthesis in chondrocytes. However, potential roles of mTORC1 in prechondrogenic mesenchyme have not been explored. In this study, we first deleted Raptor, a unique and essential component of mTORC1, in pr...

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Detalles Bibliográficos
Publicado en:J Cell Biochem
Autores principales: Jiang, Ming, Fu, Xuejie, Yang, Huilin, Long, Fanxin, Chen, Jianquan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296292/
https://ncbi.nlm.nih.gov/pubmed/27606668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25728
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