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The active spatial organization of the β-globin locus requires the transcription factor EKLF
Three-dimensional organization of a gene locus is important for its regulation, as recently demonstrated for the β-globin locus. When actively expressed, the cis-regulatory elements of the β-globin locus are in proximity in the nuclear space, forming a compartment termed the Active Chromatin Hub (AC...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529536/ https://ncbi.nlm.nih.gov/pubmed/15489291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.317004 |
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