The Erythroid Phenotype of EKLF-Null Mice: Defects in Hemoglobin Metabolism and Membrane Stability

Development of red blood cells requires the correct regulation of cellular processes including changes in cell morphology, globin expression and heme synthesis. Transcription factors such as erythroid Krüppel-like factor EKLF (Klf1) play a critical role in erythropoiesis. Mice lacking EKLF die aroun...

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Detalhes bibliográficos
Main Authors: Drissen, Roy, von Lindern, Marieke, Kolbus, Andrea, Driegen, Siska, Steinlein, Peter, Beug, Hartmut, Grosveld, Frank, Philipsen, Sjaak
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140573/
https://ncbi.nlm.nih.gov/pubmed/15923635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.12.5205-5214.2005
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