Absence of an N-Linked Glycosylation Motif in the Glycoprotein of the Live-Attenuated Argentine Hemorrhagic Fever Vaccine, Candid #1, Results in Its Improper Processing, and Reduced Surface Expression

Junin virus (JUNV), a highly pathogenic New World arenavirus, is the causative agent of Argentine hemorrhagic fever (AHF). The live-attenuated Candid #1 (Can) strain currently serves as a vaccine for at-risk populations. We have previously shown that the Can glycoprotein (GPC) gene is the primary ge...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Manning, John T., Seregin, Alexey V., Yun, Nadezhda E., Koma, Takaaki, Huang, Cheng, Barral, José, de la Torre, Juan C., Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292626/
https://ncbi.nlm.nih.gov/pubmed/28220142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados