Rescue from Cloned cDNAs and In Vivo Characterization of Recombinant Pathogenic Romero and Live-Attenuated Candid #1 Strains of Junin Virus, the Causative Agent of Argentine Hemorrhagic Fever Disease

The New World arenavirus Junin virus (JUNV) is the causative agent of Argentine hemorrhagic fever (AHF), which is associated with high morbidity and significant mortality. Several pathogenic strains of JUNV have been documented, and a highly attenuated vaccine strain (Candid #1) was generated and us...

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Detalhes bibliográficos
Main Authors: Emonet, Sebastien F., Seregin, Alexey V., Yun, Nadezhda E., Poussard, Allison L., Walker, Aida G., de la Torre, Juan C., Paessler, Slobodan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028888/
https://ncbi.nlm.nih.gov/pubmed/21123388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02102-10
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