Rescue of a Recombinant Machupo Virus from Cloned cDNAs and In Vivo Characterization in Interferon (αβ/γ) Receptor Double Knockout Mice

Machupo virus (MACV) is the etiological agent of Bolivian hemorrhagic fever (BHF), a reemerging and neglected tropical disease associated with high mortality. The prototypical strain of MACV, Carvallo, was isolated from a human patient in 1963, but minimal in vitro and in vivo characterization has b...

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Autors principals: Patterson, Michael, Seregin, Alexey, Huang, Cheng, Kolokoltsova, Olga, Smith, Jennifer, Miller, Milagros, Smith, Jeanon, Yun, Nadezhda, Poussard, Allison, Grant, Ashley, Tigabu, Bersabeh, Walker, Aida, Paessler, Slobodan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911560/
https://ncbi.nlm.nih.gov/pubmed/24284323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02925-13
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