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The Glycoprotein Precursor Gene of Junin Virus Determines the Virulence of the Romero Strain and the Attenuation of the Candid #1 Strain in a Representative Animal Model of Argentine Hemorrhagic Fever

The New World arenavirus Junin virus (JUNV) is the causative agent of Argentine hemorrhagic fever (AHF), a potentially deadly disease endemic to central regions of Argentina. The live-attenuated Candid #1 (Can) strain of JUNV is currently used to vaccinate the human population at risk. However, the...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Seregin, Alexey V., Yun, Nadezhda E., Miller, Milagros, Aronson, Judith, Smith, Jennifer K., Walker, Aida G., Smith, Jeanon N., Huang, Cheng, Manning, John T., de la Torre, Juan C., Paessler, Slobodan
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442433/
https://ncbi.nlm.nih.gov/pubmed/25810546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00104-15
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