Towards the development of activity-based probes for detection of Lysine-Specific Demethylase-1 activity

The implications of Lysine-Specific Demethylase-1 (LSD1) in tumorigenesis have urged scientists to develop diagnostic tools in order to explore the function of this enzyme. In this work, we present our efforts on the development of tranylcypromine (TCP)-based functionalized probes for activity-based...

Full description

Saved in:
Bibliographic Details
Published in:Bioorg Med Chem
Main Authors: Ourailidou, Maria E., Lenoci, Alessia, Zwergel, Clemens, Rotili, Dante, Mai, Antonello, Dekker, Frank J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292237/
https://ncbi.nlm.nih.gov/pubmed/27989416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.11.043
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items