An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases

BIX-01294 and its analogs were originally identified and subsequently designed as potent inhibitors against histone H3 lysine 9 (H3K9) methyltransferases G9a and G9a-like protein (GLP). Here we show BIX-01294 and its analog E67 can also inhibit H3K9 Jumonji demethylase KIAA1718 with half-maximal inh...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Upadhyay, Anup K., Rotili, Dante, Han, Ji Woong, Hu, Ruogu, Chang, Yanqi, Labella, Donatella, Zhang, Xing, Yoon, Young-sup, Mai, Antonello, Cheng, Xiaodong
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280428/
https://ncbi.nlm.nih.gov/pubmed/22227394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.036
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars