An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases

BIX-01294 and its analogs were originally identified and subsequently designed as potent inhibitors against histone H3 lysine 9 (H3K9) methyltransferases G9a and G9a-like protein (GLP). Here we show BIX-01294 and its analog E67 can also inhibit H3K9 Jumonji demethylase KIAA1718 with half-maximal inh...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Upadhyay, Anup K., Rotili, Dante, Han, Ji Woong, Hu, Ruogu, Chang, Yanqi, Labella, Donatella, Zhang, Xing, Yoon, Young-sup, Mai, Antonello, Cheng, Xiaodong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280428/
https://ncbi.nlm.nih.gov/pubmed/22227394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.036
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi