Novel Nonnucleoside Inhibitor of Hepatitis C Virus RNA-Dependent RNA Polymerase

A novel nonnucleoside inhibitor of hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp), [(1R)-5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyano[3,4-b]indol-1-yl] acetic acid (HCV-371), was discovered through high-throughput screening followed by chemical optimization. HCV-371 displayed broad...

詳細記述

保存先:
書誌詳細
主要な著者: Howe, Anita Y. M., Bloom, Johnathan, Baldick, Carl J., Benetatos, Christopher A., Cheng, Huiming, Christensen, Joel S., Chunduru, Srinivas K., Coburn, Glen A., Feld, Boris, Gopalsamy, Ariamala, Gorczyca, William P., Herrmann, Steve, Johann, Stephen, Jiang, Xiaoqun, Kimberland, Michelle L., Krisnamurthy, Girija, Olson, Matthew, Orlowski, Mark, Swanberg, Steve, Thompson, Ian, Thorn, Megan, Del Vecchio, Alfred, Young, Dorothy C., van Zeijl, Marja, Ellingboe, John W., Upeslacis, Janis, Collett, Marc, Mansour, Tarek S., O'Connell, John F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
Antiviral Agents
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC529219/
https://ncbi.nlm.nih.gov/pubmed/15561861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4813-4821.2004
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料