Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)

Biochemical characterization of hepatitis C virus (HCV) replication using purified, membrane-associated replication complexes is hampered by the presence of endogenous nuclease activity that copurifies with the replication complex. In this study, pulse-chase analyses were used to demonstrate that ne...

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Detalhes bibliográficos
Main Authors: Yang, Guang, Pevear, Daniel C., Collett, Marc S., Chunduru, Srinivas, Young, Dorothy C., Benetatos, Christopher, Jordan, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514995/
https://ncbi.nlm.nih.gov/pubmed/15331754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.18.10202-10205.2004
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