Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

Background: Single variant approaches have been successful in identifying DNA methylation quantitative trait loci (mQTL), although as with complex traits they lack the statistical power to identify the effects from rare genetic variants. We have undertaken extensive analyses to identify regions of l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Richardson, Tom G., Shihab, Hashem A., Hemani, Gibran, Zheng, Jie, Hannon, Eilis, Mill, Jonathan, Carnero-Montoro, Elena, Bell, Jordana T., Lyttleton, Oliver, McArdle, Wendy L., Ring, Susan M., Rodriguez, Santiago, Campbell, Colin, Smith, George Davey, Relton, Caroline L., Timpson, Nicholas J., Gaunt, Tom R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Association Studies Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291201/
https://ncbi.nlm.nih.gov/pubmed/27559110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw283
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