Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

Background: Single variant approaches have been successful in identifying DNA methylation quantitative trait loci (mQTL), although as with complex traits they lack the statistical power to identify the effects from rare genetic variants. We have undertaken extensive analyses to identify regions of l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Richardson, Tom G., Shihab, Hashem A., Hemani, Gibran, Zheng, Jie, Hannon, Eilis, Mill, Jonathan, Carnero-Montoro, Elena, Bell, Jordana T., Lyttleton, Oliver, McArdle, Wendy L., Ring, Susan M., Rodriguez, Santiago, Campbell, Colin, Smith, George Davey, Relton, Caroline L., Timpson, Nicholas J., Gaunt, Tom R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Association Studies Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291201/
https://ncbi.nlm.nih.gov/pubmed/27559110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw283
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