Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

Background: Single variant approaches have been successful in identifying DNA methylation quantitative trait loci (mQTL), although as with complex traits they lack the statistical power to identify the effects from rare genetic variants. We have undertaken extensive analyses to identify regions of l...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Richardson, Tom G., Shihab, Hashem A., Hemani, Gibran, Zheng, Jie, Hannon, Eilis, Mill, Jonathan, Carnero-Montoro, Elena, Bell, Jordana T., Lyttleton, Oliver, McArdle, Wendy L., Ring, Susan M., Rodriguez, Santiago, Campbell, Colin, Smith, George Davey, Relton, Caroline L., Timpson, Nicholas J., Gaunt, Tom R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291201/
https://ncbi.nlm.nih.gov/pubmed/27559110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw283
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