Maternal pre-pregnancy BMI and gestational weight gain, offspring DNA methylation and later offspring adiposity: findings from the Avon Longitudinal Study of Parents and Children

Background: Evidence suggests that in utero exposure to undernutrition and overnutrition might affect adiposity in later life. Epigenetic modification is suggested as a plausible mediating mechanism. Methods: We used multivariable linear regression and a negative control design to examine offspring...

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Vydáno v:Int J Epidemiol
Hlavní autoři: Sharp, Gemma C, Lawlor, Debbie A, Richmond, Rebecca C, Fraser, Abigail, Simpkin, Andrew, Suderman, Matthew, Shihab, Hashem A, Lyttleton, Oliver, McArdle, Wendy, Ring, Susan M, Gaunt, Tom R, Davey Smith, George, Relton, Caroline L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Adiposity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588865/
https://ncbi.nlm.nih.gov/pubmed/25855720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyv042
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