Assessing Oxidative Stress in Tumors by Measuring the Rate of Hyperpolarized [1-(13)C]Dehydroascorbic Acid Reduction Using (13)C Magnetic Resonance Spectroscopy

Rapid cancer cell proliferation promotes the production of reducing equivalents, which counteract the effects of relatively high levels of reactive oxygen species. Reactive oxygen species levels increase in response to chemotherapy and cell death, whereas an increase in antioxidant capacity can conf...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Timm, Kerstin N., Hu, De-En, Williams, Michael, Wright, Alan J., Kettunen, Mikko I., Kennedy, Brett W. C., Larkin, Timothy J., Dzien, Piotr, Marco-Rius, Irene, Bohndiek, Sarah E., Brindle, Kevin M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
Metabolism
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290948/
https://ncbi.nlm.nih.gov/pubmed/27994059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.761536
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